Understanding Colon Cancer

Let’s talk about something incredibly important, but often overlooked – colorectal cancer (CRC). This type of cancer affects many people, but the GREAT NEWS is that with the right knowledge and proactive steps – you can significantly reduce your risk. By understanding CRC, recognizing the risk factors, and knowing when to get screened – you can take charge of your health. Colon cancer is preventable, treatable, and beatable!

Colorectal Cancer in 2025

The American Cancer Society estimates that in 2025, the number of new colorectal cancer cases in the US will be about 106,590 for colon cancer and about 46,220 for rectal cancer.

Colorectal cancer is the second most common cause of cancer deaths for men and women combined and is expected to cause about 53,010 deaths throughout 2025.

Key Facts About Colorectal Cancer

What’s Colorectal Cancer?

Colon cancer is cancer of the colon (part of your large intestine). Rectal cancer is cancer in the rectum (the passageway that connects the colon to the anus). Together, they are colorectal.

How Common Is It?

Colon cancer is the fourth most common cancer in the U.S. and the second leading cause of cancer deaths. But don’t worry – early detection can make a huge difference.

Who Can Get It?

Anyone can get colon cancer regardless of gender, race, or nationality.

Young Adults Too

Surprisingly, 30% of colon cancer diagnoses are found in people under 55.

Survival Rates

The five-year survival rate for CRC is approximately 91% for stages I and II but declines to 13% for stage IV. Only 1 in 3 cases are diagnosed at stage I or II. The five-year overall survival rate is 64%.

Often Symptomless

Colon cancer starts as polyps and usually develops slowly for 10 to 15 years. Many people with colon cancer don’t have any symptoms at first, which is why screening is so important.

Family History and Genetic Factors

Higher Risk with Family History

If your parent, sibling, or child has had CRC, your risk is 2 to 3 times higher. Additionally, if a relative is diagnosed at a young age OR if there is more than one relative affected, the risk of developing CRC increases to 3 to 6 times that of the general population.

Family History

Start Screening Early

If CRC runs in your family, you should start screening earlier than people who do not have a family history of CRC.

Screening Options

Genetic Conditions

About 5% of people with CRC have inherited conditions like Lynch syndrome (Hereditary Non-Polyposis Colon Cancer or HNPCC), Familial Adenomatous Polyposis (FAP), or MUTYH-Associated Polyposis (MAP).

Genetics

Colorectal Cancer in Young People

 

Increasing Rates

CRC cases are rising among people under 50, approximately 13% of all CRC diagnoses are under the age of 50.

 

Daily New Cases

Each day, 56 CRC cases are diagnosed in patients ages 46 and younger.

 

Leading Cause

It’s now a leading cause of cancer death in men and the second in women under 50. Since the mid-2000s, death rates have been increasing by 2.4% per year in people younger than 50. CRC is projected to be the #1 cancer killer for young adults by the year 2030.

Late Diagnosis

Younger adults often get diagnosed later because they’re not usually screened and symptoms can be mistaken for other issues.

What About Screening?

When to Start

The recommended screening age for colorectal cancer is 45 for average risk adults. Average risk means you are 45 or older, have no family history or genetic risk factors, and are experiencing no signs or symptoms.

Why Screen?

Screening helps catch cancer early when it’s most treatable and can even prevent cancer through colonoscopies by removing polyps before they turn cancerous. Colorectal polyps are common in American adults. Anywhere between 15 and 40% of adults may have colon polyps and approximately 3.4% of polyps are pre-cancerous.

Types of Screening

Many screening options are available, including colonoscopies and other visual screening options, stool-based tests that can be done at home, and blood tests generally done in a doctor’s office.

Importance of Regular Screening

Early stages of colorectal cancer doesn’t always cause symptoms, so staying up to date with CRC screening can truly be a life saver by finding cancer earlier when it is most treatable and recovery is much faster.

Healthy Habits

Staying active, eating a balanced diet, and avoiding smoking can help reduce your risk.

Reduce Your Risk

What else?

Screening Rates

More people are getting screened. Since the mid-1980s, colorectal cancer incidence rates have declined due to increased awareness and screening, but we still have a long way to go, especially among those without health insurance. The national goal for CRC is screening is 80% in every community, currently the US has approximately a 59% screening rate.

Geographic Differences

Colorectal cancer screening, incidence, and mortality rates vary across different geographic areas mainly due to healthcare access and barriers, including screening and treatment.

Racial Disparities

Some racial and ethnic groups have higher death rates from CRC due to lower screening rates, less access to care, and lower CRC detection at its earliest stages.

The Good News

With regular screening and healthy lifestyle choices, colorectal cancer is preventable, treatable, and beatable.