Genetics and Cancer Risk: Understanding Your Family History

Understanding your family’s medical history is more than just knowing who had what illness – it’s a key part of assessing your own risk for certain cancers, including colorectal cancer. Genetics can play a big role in this, and being informed can empower you to make proactive health decisions.

How Genetics Influence Cancer Risk

Cancer is a result of changes in genes that control the way our cells function, especially how they grow and divide. While most cancers are caused by genetic changes that occur during a person’s lifetime, some people inherit abnormal genes that can increase their risk of developing cancer. This is where family history and genetics come into play.

Genetic counselors are on the front lines for hereditary cancer detection, and can be key to your care team.

Before, or even after, a cancer diagnosis, genetic counselors help evaluate your family history to understand your risk for an inherited cancer syndrome related to colorectal and other types of cancer. After evaluating this risk, they can recommend genetic testing options and then help interpret those results.

If a hereditary cancer syndrome is identified during genetic testing, genetic counselors work alongside your care team to guide you through important next steps.

  1. Education about cancer prevention and management, including
    • lifestyle modifications like diet and exercise.
    • appropriate cancer screenings.
    • other medical interventions are necessary to prevent cancer.
  2. Collaborate to provide comprehensive cancer care and help integrate genetic information into patient care. 
  3. Find and provide emotional support and resources to help patients and families cope with the emotional impact of genetic information and cancer risk. 
  4. Assisting with appropriate genetic testing for direct family members who may also be at risk for the same hereditary cancer syndrome.

Family History and Cancer Risk

If many people in your family have had colon, rectal, or other types of cancer, it could mean a higher chance of getting cancer because of your genes. This is especially true if family members were diagnosed when they were young or if cancer happened in many generations. A family history of cancer or an inherited genetic condition doesn’t mean you will get cancer, but it does mean you may be at a higher risk and should begin screening before age 45.

Family History

Genetic Testing: Should You Consider It?

Genetic testing can identify specific inherited mutations that increase the risk of cancer. If you have a strong family history of cancer, or if you are concerned about your risk, discussing genetic testing with a healthcare professional might be a good idea. It can provide valuable information for you and your family members. It can also help in making informed decisions about your health care.

What to Do if You Have a Genetic Risk for Cancer?

If genetic testing shows that you have a higher risk of cancer, there are proactive steps you can take. Regular screenings, lifestyle changes, and working closely with your healthcare team can help you stay ahead of the curve and manage your risk effectively.

Frequently Asked Questions

Why is genetic testing important?

  • Genetic testing is used to identify individuals at risk for colorectal and other cancers due to inherited genetic mutations.
  • Science is continually evolving, and some hereditary colorectal cancer-associated genes are not yet known.
  • Not everyone with a genetic mutation will develop cancer.

Who should have genetic testing?

  • If multiple family members have the same type of cancer or related cancers.
  • If there are colorectal cancer diagnoses in multiple generations of the same family.
  • A family member diagnosed with early-onset cancer (under age 50).
  • Note: not all people with a family history of colorectal cancer will need genetic testing.

Information on these pages is provided for educational purposes only. Consult your physician before making any medical decisions.

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